Infertility Female

The incidence of Female infertility is increasing rapidly because of the modern stressful lifestyle.

In today’s world more and more women are grasped by the curse of infertility. Particularly the numbers of age-related infertility are on surge as most of the women today prefer LATE MARRAIGEs or give priorities to their EDUCATION or their CAREER or they are Just Not Ready emotionally or financially to shoulder the responsibility of a child. It is important to understand that fertility declines as a woman age due to the normal age-related decrease in the number and quality of eggs that are left in their ovary.

FERTILITY AND WOMEN'S AGE

The GOLDEN PERIOD of FERTILITY or the

best reproductive years if any women are in her 20s. Fertility gradually declines in the 30s, particularly after age 35. Each month that she tries, a healthy, fertile 30-year-old woman has a 20% chance of getting pregnant.

 It is commonly understood that after menopause women are no longer able to become pregnant.

Women do not remain fertile until menopause. The average age for menopause is 47, but most women become unable to have a successful pregnancy sometime in their mid-40s. These percentages are true for natural conception as well as conception using fertility treatment, including in vitro fertilization (IVF).

The quality and the quantity of eggs gradually decline with increasing age…

NORMAL MENSTRUAL CYCLE-

The beginning of reproductive years in a female is marked by the onset of ovulation and menstruation which continues regularly each month till she attains menopause…  Every month large numbers of Eggs mature in her ovary inside of fluid-filled “follicles.” At the beginning of each menstrual cycle when a woman is having her period, a hormone called FSH (follicle-stimulating hormones) is released from the pituitary gland, in the brain. This FSH is essential for the early development and growth of the follicles. Normally, only one of those follicles will reach maturity and release an egg (ovulate); the remainder gradually will stop growing and degenerate.  If at the time of this egg release, sperms reach the fallopian tubes of female, one of the sperm fertilizes the egg to form the zygote.  Pregnancy results when this embryo implants in the inner most lining of the uterus called endometrium. If pregnancy does not occur, the endometrium is shed as the menstrual flow and the cycle begins again.

EGG QUALITY-
Women become less likely to become pregnant and more likely to have miscarriages because egg quality decreases as the number of remaining eggs dwindle in number. These changes are most noted as she reaches her MID-TO-LATE 30s. Therefore, a woman’s age is the most accurate test of egg quality. An important change in egg quality is the frequency of genetic abnormalities called ANEUPLOIDY (too many or too few chromosomes in the egg).

WHAT CAUSES FEMALE INFERTILITY?

Female infertility factors contribute to approximately 50% of all infertility cases,

The common causes of female infertility include problems with ovary or fallopian tubes or uterus, or problems with the cervix.

DISTURBANCE IN H-P-O AXIS-

  • Stress
  • Eating disorders such as anorexia or bulimia
  • Intense exercise
  • Pituitary tumours
  • Alcohol or drug use
  • Thyroid gland problems
  • Obesity

UTERINE DEFECT-

  • Congenital anomaly like Septate or Unicorn ate or Bicornuate uterus
  • DES syndrome
  • Polyps in the uterus
  • Fibroids
  • Adenomyosis
  • Intrauterine adhesions /scarring

Ovulation Defects &Decrease Ovarian reserve

  • Hormone imbalance
  • Ovarian cyst
  • Ovarian tumour
  • PCOD
  • genital TB
  • Endometrioma/Chocolate cyst
  • Radiotherapy or Chemotherapy for cancer
  • genetic syndromes causing premature ovarian failure

DAMAGE TO THE FALLOPIAN TUBES-

  • Pelvic inflammatory disease
  • Chronic infection like TB
  • previous ectopic (tubal) pregnancy
  • Endometriosis
  • Ciliary Damage

 

CERVICAL DEFECTS

  • Thickened cervical mucus
  • Cervical Stenosis
  • Congenital elongation of cervix
  • Antiserum Antibodies in cervix (Auto immune)

WHAT IS THE TEST FOR INFERTILE WOMEN?

A couple is trying for years and unsuccessful in conceiving, both partners need to go through physical and medical testing to find out the reason for her infertility, so the IVF doctor can start the process immediately.

TESTS FOR OVARIAN RESERVE-

Women with poor ovarian reserve have a lower chance of becoming pregnant than women with normal ovarian reserve in their same age group. It can be predicted by following test-

  • Basal FSH level (Day 2/3 of menses)
  • AMH (antimalaria hormone)
  • Basal Serum oestrogen levels
  • AFC (Antral Follicle Count)-It is an ultrasound assessment of total follicle number in both ovaries.

High levels of FSH or  low serum erogenous AMH level and Less AFC in ovary  indicate that ovarian reserve of the women is low and treatment should be planned accordingly.

OVULATION TESTING

To confirm ovulation is better for fertilization, the ovulation predictor kit, blood tests, and ultrasound can be performed by the doctor.

LUTEAL PHASE TESTING

This predict the IMPLANTATION POTENTIAL of the uterus by checking   the serum progesterone levels and possibly an endometrial biopsy.

ULTRASOUND TESTING

 Ultrasound tests are used throughout fertility treatment and can help answer many questions. We use ultrasound for the following tests:

  • During initial fertility testing to check the structure of the uterus and ovaries
  • For monitoring the ovaries and assessing thickness of the uterine wall throughout the menstrual cycle
  • To assess any physical abnormalities that can interfere with pregnancy

SONOSALPINGOGRAPHY (TUBAL PATENCY TEST)

  • Blocked tubes or a growth in the uterus can severely reduce your chances of getting pregnant. A Sonohysterosalpingography is an ultrasound procedure that examines the structure of the fallopian tubes and the inside walls of the uterus to check for any physical barriers to pregnancy.
  • During the procedure, a small amount of saline is inserted into the uterine cavity, which lets your doctor see the structure of the uterus using a transvaginal ultrasound.
  • The sonohysterography is done after a menstrual cycle has finished, but prior to ovulation. For most women, this is between days 6 to 11 of the menstrual cycle.

DIAGNOSTIC HYSTEROSCOPY-

 Hysteroscopy means examining the inside of the uterus, with a narrow telescope, to determine the cause of infertility. This procedure is performed under intravenous sedation to avoid discomfort. If something is found that could affect your fertility such as polyps, fibroids, adhesions or septum, it can be treated at the same time .

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 DIAGNOSTIC LAPAROSCOPY

Laparoscopy is the gold standard test to assess the patency of a  fallopian tubes .It  involves the insertion of a thin diagnostic telescope through the navel (belly button) and one to three small incisions elsewhere for manipulation under general anaesthesia. With the help of laproscopy,your doctor can diagnose  and treat conditions that could be affecting your fertility such as fibroid uterus , endometriosis and pelvic adhesions.

  • SPECIALIZED  IVF DOCTORS     

who gives you complete care that makes your tough time even positive and relaxing.

  • TRAINED MEDICAL STAFFS ready to give their best in making the case successful.
  • MODERN LAB EQUIPMENT

Our IVF hospital features State of the art infrastructure, patient-friendly environment, and modern most advanced IVF and Andrology Laboratory as well as equipment leading to increase chances of conceiving.

  • With regards to MAINTAINING WOMEN’S PRIVACY we make sure that every patient is always well attended doctors and staff so that they can talk comfortably.
In case of any queries about male fertility, treatment options, Visit Dr. Neha Singh at I Gorakhpur. Follow her on Facebook, Instagram, Twitter, YouTube channel, and LinkedIn
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